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#transcriptomics

1 post1 participant0 posts today
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Bioinfo-fr.net

📰 Aujourd'hui, Gwenaelle nous partage l'histoire des technologies de transcriptomique : comment faisait-on avant l'ère bénie du séquençage haut débit 🤔
bioinfo-fr.net/expression-de-g
#bioinfofr #transcriptomics

Bioinfo-fr.net · Comment l'étude des intensités d'expression de gène a évolué avec les technologies de transcriptomique ? - Bioinfo-fr.netCet article est en par­tie basé sur mon intro­duc­tion de thèse [0], refor­ma­tée pour conve­nir au for­mat du blog et agré­men­tée des nou­velles infor­ma­tions pour ne pas être un simple cata­logue de connais­sances. Qu'il s'agisse du génome entier, du génome de tis­sus ou du génome de cel­lules spé­ci­fiques, l'étude de la quan­ti­té de trans­crits pro­duits, […]
Public
Ana Viñuela

Casey Brown was a great scientist and an amazing person. He could always make time to catch up with junior people, give encouragement or just joke about pretty much everything.

Now in his honour some of the leading scientist in #genomics and #complextraits have joint to record the Casey Brown #lectures.

From the basics of human #genetics, to #transcriptomics #epigenetics or #machinelearning for genomics. All free to watch.

m.youtube.com/playlist?list=PL

m.youtube.comBefore you continue to YouTube
Public
Arli A P

Greetings to i3L students and all life sciences enthusiasts!

i3L proudly presents another episode of Power Talk!

Special in December 2024 Power Talk, i3L proudly invites an expert: Rizky Nurdiansyah .,M.Si (PhD Candidate at Centre for Microbiome Research, School of Biomedical Sciences, Queensland University of Technology (QUT))

Register Here: link : lnkd.in/gVxJ7v5c

We're looking forward to seeing you! 🙏 🙏 🙏
metagenomics #i3L #biotechnology #biomedicine #genomics #transcriptomics

Public
Albert Cardona

"Whole-embryo Spatial Transcriptomics at Subcellular Resolution from Gastrulation to Organogenesis", by Wan et al. 2024
biorxiv.org/content/10.1101/20

bioRxiv · Whole-embryo Spatial Transcriptomics at Subcellular Resolution from Gastrulation to OrganogenesisSpatiotemporal patterns of gene expression underlie embryogenesis. Despite progress in single-cell genomics, mapping these patterns across whole embryos with comprehensive gene coverage and at high resolution has remained elusive. Here, we introduce a whole-embryo imaging platform using multiplexed error-robust fluorescent in-situ hybridization (weMERFISH). We quantified the expression of 495 genes in whole-mount zebrafish embryos at subcellular resolution. Integration with single-cell multiomics data generated an atlas detailing the expression of 25,872 genes and the accessibility of 294,954 chromatin regions, explorable with an online interface MERFISHEYES (beta version). We found that temporal gene expression aligns with cellular maturation and morphogenetic movements, diverse expression patterns correspond to composites of tissue-specific accessible elements, and changes in gene expression generate sharp boundaries during gastrulation. These results establish a novel approach for whole-organism spatial transcriptomics, provide a comprehensive spatially resolved atlas of gene expression and chromatin accessibility, and reveal the diversity, precision and emergence of embryonic patterns. ### Competing Interest Statement The authors have declared no competing interest.
#zebrafish#RNAseq#transcriptomics
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