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#curcumin

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@untilted

Same. Like a lot of #ActuallyAutistic people, I don't sleep well, and #CBD shortly before bed helps. In fact, I started taking CBD soon after it became legal here, some years before I knew I was autistic.

I now use oil rather than capsules, because oil gives me finer control over the dose and it works out cheaper than other formats. You do have to be careful not to spill it on your top, though: it stains.

I've used #GinkgoBiloba for several decades. It sharpens both my reactions and my cognition.

I take #curcumin for other reasons, but I find it improves my working memory and my digestion as well. Simple turmeric is poorly absorbed and often contaminated with lead, so anyone wanting to experiment with it would be well advised to use a modern, safer, more bioavailable preparation.

@Psychonaut @actuallyautistic @actuallyadhd

#Curcumin has been identified as a promising antitumor compound capable of suppressing tumor initiation, promotion, invasion, and metastasis

The anticarcinogenic effects of curcumin are attributed to an increase in the activation of macrophages and NK cells

Curcumin treatment lowers histone acetylation (hypoacetylation) by inhibiting the HAT (Histone acetyltransferase) activity without an effect on the HDAC activity

link.springer.com/chapter/10.1

SpringerLinkThe Food as an Antioxidant SystemThe science of nutrition is a developing multidiscipline sector. Oxidative stress and chronic inflammation are the consequences of unhealthy eating habits. On the contrary, food could be a source of different antioxidant molecules that influence redox balance,...

Quite an illustrative case of food supplement industry and alt-med parasitizing on genuine medical research:

Aggarwal was particularly drawn to curcumin, a non-toxic compound found in turmeric that has long been staple in Ayurvedic systems of medicine. He authored more than 120 articles about the compound from 1994 to 2020. These articles reported that curcumin had therapeutic potential for a variety of diseases, including various cancers, Alzheimer’s disease and, more recently, COVID-19. MD Anderson Cancer Center initially appeared to be fully on board with Aggarwal’s work. At one point, their website’s FAQ page recommended visitors buy curcumin wholesale from a company for which Aggarwal was a paid speaker (see “Spice Healer”, Scientific American). However, in 2012 (following observations of image manipulation raised by pseudonymous sleuth Juuichi Jigen), MD Anderson Cancer Center launched a research fraud probe against Aggarwal which eventually led to 30 of Aggarwal’s articles being retracted.

https://reeserichardson.blog/2024/01/30/the-king-of-curcumin-a-case-study-in-the-consequences-of-large-scale-research-fraud/

Reese Richardson · The King of Curcumin: a case study in the consequences of large-scale research fraudCould the fraudulent work of one researcher be responsible for the rise of curcumin research?

The massive die-offs of the global coral reefs should be a concern to all of us.

With the increasing ocean temperatures causing coral bleaching due to a symbiosis breakdown between coral polyps and algae, research on how to prevent this is ongoing.

Italian scientists have found that using antioxidants, like curcumin, to combat the reactive oxygen species (ROS) accumulation causing bleaching protects the coral symbiosis.

#Coral #Symbiosis #Curcumin #Science #Scicomm

pubs.acs.org/doi/10.1021/acsam