Shingrix, The Shingles Vaccine, Could Reduce Your Risk Of Dementia
"The new recombinant shingles vaccine, ‘Shingrix,’ is associated with a reduced risk of dementia compared to an earlier shingles vaccine, according to a major new study."
by @grrlscientist via #Substack
#Vaccines #Shingrix #dementia #healthcare #SciComm https://grrlscientist.substack.com/p/shingrix-the-shingles-vaccine-could
Shingrix, The Shingles Vaccine, Could Reduce Your Risk Of Dementia
"The new recombinant shingles vaccine, ‘Shingrix,’ is associated with a reduced risk of dementia compared to an earlier shingles vaccine, according to a major new study."
by @GrrlScientist via #Substack
#Vaccines #Shingrix #dementia #healthcare #SciComm https://grrlscientist.substack.com/p/shingrix-the-shingles-vaccine-could
Shingles vaccine linked to reduction in dementia diagnoses, study finds
Wow!
'Study finds strongest evidence yet that shingles vaccine helps cut dementia risk'
"Health records of more than 280,000 older adults revealed that those who received a largely discontinued shingles vaccine called Zostavax were 20% less likely to be diagnosed with dementia over the next seven years than those who went without."
"a 20% reduction in dementia risk, with the strongest effect in women"
"Last year, Oxford researchers reported an even stronger protective effect in people who received Shingrix, a newer vaccine."
I'm the polar opposite of anti-vaxx. I'm a #VaxxtotheMax person.
I started nursing in the mid-70's & we were vaxxed for everything known to mankind. Felt a bit crook after the #smallpox but otherwise, not a problem.
Have had 7 #COVID19 vaxx without an issue (haven't had COVID as far as I know).
One #Shingles vaccine & 6 months to the day later, still suffering the side effects.
If you're considering #Shingrix please talk to your doc about side effects.
Tip: misschien dat Shingrix gezamenlijk inkopen met Duitsland, Frankrijk en VK (in combinatie met de toenemende vergrijzing) tot dezelfde beleidsmatige uitkomst in Nederland leidt. Want daar is het blijkbaar wèl kosteneffectief.
“Voorkomen via vaccins is de effectiefste optie. In onder meer Duitsland, Frankrijk en het Verenigd Koninkrijk worden de vaccins wel vergoed.”
#Gordelroos
#Shingrix
#Vaccin
#Vergoeding
#PostherpetischeNeuralgie
#Vergrijzing
#Gezondheidsraad
Singles and pneumonia shots today. I did not know that if you've had shingles before, there is a 30% higher risk for stroke/heart attack. I had shingles as a teen, as did my youngest daughter. So, the old vaccine didn't address the cardiovascular threat. The new one does. Even if you've had the old vaccine, get the new one. Shingles can also cause blindness. Don't ignore it, folks. (Boost please!)
I'm fully vaxxed. I haven't had #COVID19 as far as I'm aware (but of course, I might have...). Just spent a week in a cardiac unit with atypical chest pain, sinus tachy on slightest exertion and at rest, and some other symptoms. Clear for PE, echo normal, no ECG changes, no troponin rise, normal coronary arteries.
The medical team never asked if I'd had COVID, never even mentioned it.
(I had, however, recently had the #Shingrix vaccine, which looks like it might be the cause.)
Shingrix, The Shingles Vaccine, Could Reduce Your Risk Of Dementia
"The new recombinant shingles vaccine, ‘Shingrix,’ is associated with a reduced risk of dementia compared to an earlier shingles vaccine, according to a major new study."
by @grrlscientist via @medium
#Shingrix #vaccines #microbiology #viruses #dementia #SciComm https://medium.com/grrlscientist/shingrix-the-shingles-vaccine-could-reduce-your-risk-of-dementia-0e3632822c7e
Soreness is nearly all gone. I have a slightly swollen pink blotch still, at the vaccination site. It's warm to the touch and slightly itchy. And is slowly fading. So seems like that's the worst of it for this one. Shall see if the second in a few months time is like this.
Arm still sore, have a pink raised blotch with slight swelling in injection site. But that's it so far, manageable with ibuprofen and paracetamol.
So far arm is sore, but that's it for any side effects. Hopefully this continues.
Researching the shingles vaccine, #Shingrix. Manufacturer’s website and CDC website both say not to get it if you are allergic to any of the ingredients…. But do they provide links to a page listing the ingredients so you can check what they are? Of course not, that would be far too sensible. You have to manually hunt down the pdf of the package insert on the FDA website and scroll to p15 https://www.fda.gov/vaccines-blood-biologics/vaccines/shingrix
Oof this #Shingrix immunization is dong a number on my arm! Generally ok and I'm weathering it fine since yesterday's shot but I seem to have grown an additional bicep. Glad I got it though! I had very mild chickenpox as a kid and I'd rather keep neuralgia away
#GetVaccinated
https://www.cdc.gov/vaccines/vpd/shingles/public/shingrix/index.html
A vaccine that could lower dementia risk has been hiding in plain sight
Why the vaccine may protect against dementia
Offit and other experts said there are two possible reasons that the #shingles vaccine might protect against dementia. First, previous research suggests that herpes infection might play a role in the development of #dementia
#Shingrix dramatically decreases the reactivation of the herpes virus that causes chickenpox
Experts also hypothesize there might be something about the particular way Shingrix stimulates the body’s immune system against shingles that decreases the chances of dementia”
https://www.washingtonpost.com/wellness/2024/07/30/shingles-vaccine-lower-dementia-risk/
Shingrix, The Shingles Vaccine, Could Reduce Your Risk Of Dementia, study out of University of Oxford, published by Nature Medicine
#Vaccines
#shingles
#virus #Shingrix #dementia #PublicHealth
#Healthcare
#SciComm
https://www.forbes.com/sites/grrlscientist/2024/07/28/shingrix-the-shingles-vaccine-could-reduce-your-risk-of-dementia/
Study raises hopes that 
shingles vaccine may delay onset of dementia 
Researchers have raised hopes for
delaying dementia after finding that a recently approved shingles vaccine was linked to a substantial reduction in diagnoses of the condition in the six years after receiving the shot.
The discovery, based on US medical records, suggests that beyond the health benefits of preventing shingles, a painful and sometimes serious condition in elderly people, 
the vaccine may also delay the onset of dementia, the UK’s leading cause of death.
Dr Maxime Taquet at the University of Oxford, the first author on the study, said the results supported the idea that shingles vaccination may prevent dementia.
“If validated in clinical trials, these findings could have significant implications for older adults, health services, and public health.”
Shingles is caused by the herpes zoster virus and can flare up in people who have previously had chickenpox.
When a shingles vaccine, #Zostavax, was first rolled out in 2006, a number of studies found hints that the risk of dementia seemed to be lower in those who got the shots.
The development of a new and more effective shingles vaccine, #Shingrix, led to a rapid switch in the US in October 2017, meaning those who were vaccinated before that date received Zostavax, while those vaccinated after tended to have Shingrix.
The Oxford team studied the health records of more than 200,000 US citizens vaccinated for shingles, about half of whom received the new vaccine. 
Over the next six years, the risk of dementia was 17% lower in those who received Shingrix compared with Zostavax.
For those who went on to develop dementia, that amounts to an extra 164 days, or nearly six months, lived without the condition.
The effect was stronger in women, at 22%, than in men at 13%.
The researchers went on to examine dementia rates in people who received other vaccines. Writing in Nature Medicine,
they describe how those given Shingrix had a 23 to 27% lower risk of dementia than people who were vaccinated against flu, tetanus, diphtheria or pertussis.
One of the authors of the study, Prof John Todd at Oxford, is a consultant to GSK, the manufacturer of Shingrix, but the researchers said the study was conducted without any involvement from the pharma company, who were informed of the work when it was accepted for publication.
Last year, the NHS made Shingrix available to people turning 65. “The expectation is that if this is indeed a causal effect, then we would see a reduction in dementia in the UK once people start taking up the Shingrix vaccine,” said Taquet.
There are more than 55 million people globally living with dementia and more than 900,000 in the UK alone.
One in three people will develop the condition in their lifetime, and while drugs that appear to slow the disease have recently been approved, there is no cure.
Got first round of shingles vaccination yesterday. If your health plan pays (or even if not) it's very effective apparently and I can speak from experience shingles even if a "mild" case is nasty and something you definitely want to avoid.
Mechanic 
