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CellBioNewsThis sea worm's posterior swims away, and now scientists know how.<a href="https://scientificnetwork.de/tags/HOX" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#HOX</a> <a href="https://scientificnetwork.de/tags/gene_expression" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#gene_expression</a> <a href="https://phys.org/news/2023-11-sea-worm-posterior-scientists.html" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://phys.org/news/2023-11-sea-worm-posterior-scientists.html</a>

Marc Robinson-RechaviThe cool <a href="https://ecoevo.social/tags/evodevo" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#evodevo</a> paper everyone is talking about: Molecular evidence of anteroposterior patterning in adult echinoderms "This finding suggests that from the perspective of ectoderm patterning, echinoderms are mostly head-like animals and provides a developmental rationale for the re-evaluation of the events that led to the evolution of the derived adult body plan of echinoderms." <a href="https://www.nature.com/articles/s41586-023-06669-2" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://www.nature.com/articles/s41586-023-06669-2</a> <a href="https://ecoevo.social/tags/hox" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#hox</a> <a href="https://ecoevo.social/tags/echinoderm" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#echinoderm</a> <a href="https://ecoevo.social/tags/seastar" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#seastar</a>

CellBioNewsHow do <a href="https://scientificnetwork.de/tags/caterpillars" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#caterpillars</a> acquire chubby <a href="https://scientificnetwork.de/tags/legs" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#legs</a>? Scientists trace the origins to a <a href="https://scientificnetwork.de/tags/genetic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#genetic</a> program associated with <a href="https://scientificnetwork.de/tags/crabs" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#crabs</a>.<a href="https://scientificnetwork.de/tags/prolegs" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#prolegs</a> <a href="https://scientificnetwork.de/tags/Hox" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Hox</a> <a href="https://scientificnetwork.de/tags/abdominal_A" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#abdominal_A</a> <a href="https://scientificnetwork.de/tags/mRNA" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#mRNA</a> <a href="https://scientificnetwork.de/tags/transcriptomics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#transcriptomics</a><a href="https://phys.org/news/2023-10-caterpillars-chubby-legs-scientists-genetic.html" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://phys.org/news/2023-10-caterpillars-chubby-legs-scientists-genetic.html</a>

neville parkSo I was rereading a cool arachnid evo-devo paper, and I wondered…Could you make a simple "animal" as a web page, using <a href="https://flipping.rocks/tags/CSS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#CSS</a> and <a href="https://flipping.rocks/tags/HTML" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#HTML</a> as <a href="https://flipping.rocks/tags/Hox" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Hox</a> genes and body plan, so that people could tweak things using browser dev tools to hide/duplicate/alter the presentation of elements, the way scientists knock down or upregulate genes to see what it does to the animal?Evo-devo stuff has always reminded me of using "display: none !important" or "border: 1px solid red" to figure out what CSS rules do. And like CSS Zen Garden—radically altering the look of a page with CSS without touching the HTML.<a href="https://flipping.rocks/tags/EvoDevo" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#EvoDevo</a> <a href="https://flipping.rocks/tags/WebDev" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#WebDev</a> <a href="https://flipping.rocks/tags/appendages" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#appendages</a>

Sally LowellNotch activation revealed to be an important stepping stone on the path to acquiring anterior-posterior identity and mesodermal fate during axis elongation.Very interesting work from <a href="https://mas.to/@a_tsakiridis" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@a_tsakiridis</a>, Fay Cooper & colleagues in Sheffield using human pluripotent cell-based models, plus some lovely chick embryo grafting data from Kim Dale's lab in Dundee<a href="https://biologists.social/tags/PaperThemeTune" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#PaperThemeTune</a> "I'm Notch Your Stepping Stone" by the Monkees<a href="https://biologists.social/tags/DevBio" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#DevBio</a> <a href="https://biologists.social/tags/StemCells" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#StemCells</a> <a href="https://biologists.social/tags/Hox" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Hox</a> <a href="https://biologists.social/tags/Notch" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Notch</a> <a href="https://biologists.social/tags/NMPs" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#NMPs</a><a href="https://www.biorxiv.org/content/10.1101/2023.06.16.545269v1" rel="nofollow noopener noreferrer" target="_blank">https://www.biorxiv.org/content/10.1101/2023.06.16.545269v1</a>

CellBioNews<a href="https://scientificnetwork.de/tags/Embryoids" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Embryoids</a> shed light on a complex <a href="https://scientificnetwork.de/tags/genetic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#genetic</a> mechanism.<a href="https://scientificnetwork.de/tags/genomics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#genomics</a> <a href="https://scientificnetwork.de/tags/HOX" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#HOX</a> <a href="https://scientificnetwork.de/tags/CTCF" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#CTCF</a><a href="https://phys.org/news/2023-06-embryoids-complex-genetic-mechanism.html" rel="nofollow noopener noreferrer" target="_blank">https://phys.org/news/2023-06-embryoids-complex-genetic-mechanism.html</a>

Sally LowellNotch activation revealed to be an important stepping stone on the path to acquiring anterior-posterior identity and mesodermal fate during axis elongation.Very interesting work from <a href="https://mas.to/@a_tsakiridis" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@a_tsakiridis</a>, Fay Cooper & colleagues in Sheffield using human pluripotent cell-based models, plus some lovely chick embryo grafting data from Kim Dale's lab in Dundee<a href="https://mas.to/tags/PaperThemeTune" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#PaperThemeTune</a> "I'm Notch Your Stepping Stone" by the Monkees<a href="https://mas.to/tags/DevBio" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#DevBio</a> <a href="https://mas.to/tags/StemCells" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#StemCells</a> <a href="https://mas.to/tags/Hox" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Hox</a> <a href="https://mas.to/tags/Notch" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Notch</a> <a href="https://mas.to/tags/NMPs" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#NMPs</a><a href="https://www.biorxiv.org/content/10.1101/2023.06.16.545269v1" rel="nofollow noopener noreferrer" target="_blank">https://www.biorxiv.org/content/10.1101/2023.06.16.545269v1</a>

Albert CardonaFantastic talk today by <a href="https://mas.to/@DenisDuboule" class="u-url mention">@DenisDuboule</a> at the <a href="https://mathstodon.xyz/tags/MRCLMB" class="mention hashtag" rel="tag">#MRCLMB</a> on <a href="https://mathstodon.xyz/tags/Hox" class="mention hashtag" rel="tag">#Hox</a> genes, highlighting their unique features and introducing the resolution of a long-standing mystery: the Hox timer. As explained in:"Sequential And Directional Insulation By Conserved CTCF Sites Underlies The Hox Timer In Pseudo-Embryos", Rekaik et al. 2022 <a href="https://www.biorxiv.org/content/10.1101/2022.08.29.505673v1" target="_blank" rel="nofollow noopener noreferrer" translate="no">https://www.biorxiv.org/content/10.1101/2022.08.29.505673v1</a><a href="https://mathstodon.xyz/tags/DevBio" class="mention hashtag" rel="tag">#DevBio</a> <a href="https://mathstodon.xyz/tags/gastruloids" class="mention hashtag" rel="tag">#gastruloids</a>

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