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#cannabinoid

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JADe (he, him)<p>ENG: Today, first saturday in May, hundreds of thousands will march not just for a plant, but for personal freedom, civil rights, a culture of peace and taking better care for people in their family/community without Big Pharma synthetic poison. Check a better <a href="https://mastodon.cr/tags/cannabis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cannabis</span></a> ointment recipe backed by science in my latest blog entry: </p><p><a href="https://jorge--alban--dobles-blogspot-com.translate.goog/?m=1&amp;_x_tr_sl=es&amp;_x_tr_tl=en&amp;_x_tr_hl=es-419&amp;_x_tr_pto=wapp" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">jorge--alban--dobles-blogspot-</span><span class="invisible">com.translate.goog/?m=1&amp;_x_tr_sl=es&amp;_x_tr_tl=en&amp;_x_tr_hl=es-419&amp;_x_tr_pto=wapp</span></a></p><p>ESP: Hoy, primer sábado de mayo, cientos de miles de personas marcharán no solo por una planta, sino en defensa de libertad personal, los derechos civiles, una cultura de paz y la posibilidad de mejorar la saluds de su familia/comunidad ni los venenos sintéticos de Nig Pharma. Para una mejor receta de ungüento de <a href="https://mastodon.cr/tags/marijuana" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>marijuana</span></a> ,respaldada por la ciencia, vean la última entrada en:</p><p><a href="https://jorge-alban-dobles.blogspot.com/?m=1" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">jorge-alban-dobles.blogspot.co</span><span class="invisible">m/?m=1</span></a></p><p><a href="https://mastodon.cr/tags/cannabinoid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cannabinoid</span></a> <a href="https://mastodon.cr/tags/thc" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>thc</span></a> <a href="https://mastodon.cr/tags/cbd" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cbd</span></a> <a href="https://mastodon.cr/tags/cbn" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cbn</span></a> <a href="https://mastodon.cr/tags/regenerativemedicine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>regenerativemedicine</span></a> <a href="https://mastodon.cr/tags/maconha" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>maconha</span></a> <a href="https://mastodon.cr/tags/mota" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>mota</span></a> <a href="https://mastodon.cr/tags/medicinal" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>medicinal</span></a> <a href="https://mastodon.cr/tags/civilrights" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>civilrights</span></a> <a href="https://mastodon.cr/tags/freedom" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>freedom</span></a> <a href="https://mastodon.cr/tags/peace" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>peace</span></a> <a href="https://mastodon.cr/tags/weed" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>weed</span></a> <a href="https://mastodon.cr/tags/marchamundialmari" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>marchamundialmari</span></a> <a href="https://mastodon.cr/tags/marihuana" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>marihuana</span></a></p>
EURACTIV Health<p>Denmark and Sweden see rise in semisynthetic <a href="https://eupolicy.social/tags/cannabinoid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cannabinoid</span></a> poisonings <a href="https://www.euractiv.com/section/health-consumers/news/denmark-and-sweden-see-rise-in-semisynthetic-cannabinoid-poisonings/?utm_source=dlvr.it&amp;utm_medium=mastodon" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">euractiv.com/section/health-co</span><span class="invisible">nsumers/news/denmark-and-sweden-see-rise-in-semisynthetic-cannabinoid-poisonings/?utm_source=dlvr.it&amp;utm_medium=mastodon</span></a></p>
Euractiv<p>Denmark and Sweden see rise in semisynthetic <a href="https://masto.ai/tags/cannabinoid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cannabinoid</span></a> poisonings: <a href="https://masto.ai/tags/Cannabinoid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Cannabinoid</span></a>-induced poisonings are leading to more hospital admissions as drug traffickers target puff bars, <a href="https://masto.ai/tags/gummies" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>gummies</span></a>, and <a href="https://masto.ai/tags/ecigarettes" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>ecigarettes</span></a>. <a href="https://www.euractiv.com/section/health-consumers/news/denmark-and-sweden-see-rise-in-semisynthetic-cannabinoid-poisonings/?utm_source=mastodon&amp;utm_medium=dlvr.it" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">euractiv.com/section/health-co</span><span class="invisible">nsumers/news/denmark-and-sweden-see-rise-in-semisynthetic-cannabinoid-poisonings/?utm_source=mastodon&amp;utm_medium=dlvr.it</span></a></p>
JADe (he, him)<p><span class="h-card" translate="no"><a href="https://paquita.masto.host/@Kyol" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>Kyol</span></a></span> </p><p>Hola. Yo hago "marigüanol" para mi madre de 82, que también padece de artrosis. Hace un par de años tuvo una caída y ahora lleva prótesis de titanio en muñeca y tobillo.</p><p>Este ungüento de CBN + CBD le ayuda a dormir sin dolor.</p><p>El Cannabinol (CBN) es activador de receptores CB2, con mayor presencia en hígado, periferia del cuerpo, sistema inmune, piel y huesos. </p><p>El CBD es necesario modulador pero como explica este estudio, el control del dolor (analgesia) es mayor si ambos CBN y CBD están presentes en cantidades parecidas. Cuando domina el CBD el efecto analgésico se reduce. </p><p><a href="https://www.sciencedirect.com/science/article/abs/pii/S0003996919302249" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">sciencedirect.com/science/arti</span><span class="invisible">cle/abs/pii/S0003996919302249</span></a></p><p>Este ungüento se produce al cocer flor "recreativa" equilibrada 1:1 o al menos de tipo indica, en aceite de oliva o aguacate a 90 C por 60 minutos. Una vez cocida pasas esta mezcla por filtros de papel para café. Ya limpia sin materia vegetal la mezclas con una parte igual de manteca de cacao derretida y calientas de nuevo, agitando constantemente hasta emparejar.</p><p>Yo uso 4 gr de flor seca desmenuzada por cada 100 ml de aceite. Los tiempos y temperaturas deben respetarse, pues se basan en la Calculadora de Preservación del Cannabis mezcla, y cambia si en la mezcla domina THCA, THC o CBN, lo que cambia el efecto. </p><p><a href="https://metrology.shinyapps.io/cannabis-calculator/" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">metrology.shinyapps.io/cannabi</span><span class="invisible">s-calculator/</span></a></p><p>Pej el THCA que domina en flor "recreativa" cruda no provoca volazón, pero es ansiolítico, neuroprotector, antiespasmódico, antiemético y desinflamante. Razono todas sus propiedades comprobadas y explico su uso como tisana en mi blog:</p><p><a href="https://jorge-alban-dobles.blogspot.com/2023/07/bombo-cannabinoides-acidos-y-longevidad.html?m=1" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">jorge-alban-dobles.blogspot.co</span><span class="invisible">m/2023/07/bombo-cannabinoides-acidos-y-longevidad.html?m=1</span></a></p><p>El THC que domina en flor ligeramente tostada o descarboxilada, es el único realmente psicotrópico, pero el más analgésico y anticancerígeno de todos.</p><p>El CBN de la flor cocida, ideal para el ungüento tópico, además de analgésico, es neuroprotector, anti insomnio, destruye superbacterias y atrae células madre de la médula para reparar fracturas y mejorar densidad ósea. </p><p>No venta ni distribución, solo educación sobre el tema.</p><p><a href="https://mastodon.cr/tags/medicinalplant" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>medicinalplant</span></a> <a href="https://mastodon.cr/tags/cannabis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cannabis</span></a> <a href="https://mastodon.cr/tags/thc" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>thc</span></a> <a href="https://mastodon.cr/tags/cbd" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cbd</span></a> <a href="https://mastodon.cr/tags/cbn" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cbn</span></a> <a href="https://mastodon.cr/tags/cannabismedicinal" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cannabismedicinal</span></a> <a href="https://mastodon.cr/tags/cannabinoid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cannabinoid</span></a> <a href="https://mastodon.cr/tags/weed" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>weed</span></a> <a href="https://mastodon.cr/tags/marihuana" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>marihuana</span></a></p>
Chefkoch77<p><a href="https://chaos.social/tags/VapersOfFedi" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>VapersOfFedi</span></a> <a href="https://chaos.social/tags/VapersOfMastodon" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>VapersOfMastodon</span></a> <a href="https://chaos.social/tags/Cannabinoid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Cannabinoid</span></a> <a href="https://chaos.social/tags/Vape" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Vape</span></a> <a href="https://chaos.social/tags/Vapers" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Vapers</span></a> <a href="https://chaos.social/tags/Vaporizer" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Vaporizer</span></a> </p><p>Temperatur</p><p>THC-A 105°C<br>CBD-A 120°C<br>THC 157°C<br>CBD 180°C<br>CBN 185°C<br>CBC 220°C</p><p>Verbrennung 230°C</p>
nemo™ 🇺🇦<p><a href="https://mas.to/tags/Synthetic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Synthetic</span></a> <a href="https://mas.to/tags/Biology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Biology</span></a>: The Next Step in the <a href="https://mas.to/tags/Cannabinoid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Cannabinoid</span></a> Revolution</p><p><a href="https://www.labiotech.eu/in-depth/cannabinoid-synthetic-biology/" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">labiotech.eu/in-depth/cannabin</span><span class="invisible">oid-synthetic-biology/</span></a></p><p><a href="https://mas.to/tags/nemoradio" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>nemoradio</span></a></p>
DoomsdaysCW<p><a href="https://kolektiva.social/tags/Cannabinoids" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Cannabinoids</span></a> as novel <a href="https://kolektiva.social/tags/AntiInflammatory" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>AntiInflammatory</span></a> drugs</p><p>by Prakash Nagarkatti, et al.<br>October, 2009</p><p>Abstract:</p><p>"Cannabinoids are a group of compounds that mediate their effects through cannabinoid receptors. The discovery of Δ9-tetrahydrocannabinol (<a href="https://kolektiva.social/tags/THC" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>THC</span></a>) as the major psychoactive principle in marijuana, as well as the identification of <a href="https://kolektiva.social/tags/cannabinoid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cannabinoid</span></a> receptors and their endogenous ligands, has led to a significant growth in research aimed at understanding the physiological functions of cannabinoids. Cannabinoid receptors include CB1, which is predominantly expressed in the brain, and CB2, which is primarily found on the cells of the immune system. The fact that both CB1 and CB2 receptors have been found on <a href="https://kolektiva.social/tags/immune" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>immune</span></a> cells suggests that cannabinoids play an important role in the regulation of the immune system. Recent studies demonstrated that administration of THC into mice triggered marked apoptosis in T cells and dendritic cells, resulting in immunosuppression. In addition, several studies showed that cannabinoids downregulate <a href="https://kolektiva.social/tags/cytokine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cytokine</span></a> and chemokine production and, in some models, upregulate T-regulatory cells (Tregs) as a mechanism to suppress <a href="https://kolektiva.social/tags/inflammatory" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>inflammatory</span></a> responses. The <a href="https://kolektiva.social/tags/endocannabinoid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>endocannabinoid</span></a> system is also involved in <a href="https://kolektiva.social/tags/immunoregulation" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>immunoregulation</span></a>. For example, administration of endocannabinoids or use of inhibitors of enzymes that break down the endocannabinoids, led to immunosuppression and recovery from immune-mediated injury to organs such as the liver. Manipulation of endocannabinoids and/or use of exogenous cannabinoids in vivo can constitute a potent treatment modality against inflammatory disorders. This review will focus on the potential use of cannabinoids as a new class of anti-inflammatory agents against a number of inflammatory and autoimmune diseases that are primarily triggered by activated T cells or other cellular immune components."</p><p>Executive summary</p><p>- Cannabinoids, the active components of <a href="https://kolektiva.social/tags/CannabisSativa" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>CannabisSativa</span></a>, and endogenous cannabinoids mediate their effects through activation of specific cannabinoid receptors known as cannabinoid receptor 1 and 2 (CB1 and CB2).</p><p>- The cannabinoid system has been shown both in vivo and in vitro to be involved in regulating the immune system through its immunomodulatory properties.</p><p>- Cannabinoids suppress inflammatory response and subsequently attenuate disease symptoms. This property of cannabinoids is mediated through multiple pathways such as induction of apoptosis in activated immune cells, suppression of cytokines and chemokines at inflammatory sites and upregulation of FoxP3+ regulatory T cells.</p><p>- Cannabinoids have been tested in several experimental models of autoimmune disorders such as <a href="https://kolektiva.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>MultipleSclerosis</span></a>, <a href="https://kolektiva.social/tags/RheumatoidArthritis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>RheumatoidArthritis</span></a>, <a href="https://kolektiva.social/tags/colitis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>colitis</span></a> and <a href="https://kolektiva.social/tags/hepatitis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>hepatitis</span></a> and have been shown to protect the host from the pathogenesis through induction of multiple anti-inflammatory pathways.</p><p>- Cannabinoids may also be beneficial in certain types of <a href="https://kolektiva.social/tags/cancers" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cancers</span></a> that are triggered by <a href="https://kolektiva.social/tags/ChronicInflammation" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>ChronicInflammation</span></a> In such instances, cannabinoids can either directly inhibit tumor growth or suppress inflammation and tumor angiogenesis.</p><p><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828614/" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">ncbi.nlm.nih.gov/pmc/articles/</span><span class="invisible">PMC2828614/</span></a></p>
Getzler Lab at KenyonCollege<p>Reading a student capstone paper about synthetic <a href="https://mstdn.science/tags/cannabinoid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cannabinoid</span></a> receptor agonists and the author notes that "Efficacy can also be determined in vivo by radiobiotelemmetry, which can quantify physiological levels of the 'cannabinoid tetrad' (i.e. hypothermia, analgesia, hypolocomotion, and catalepsy)." This has got to be the most sciency way ever of saying that you can tell if the person is really high. <a href="https://mstdn.science/tags/chemistry" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>chemistry</span></a> <a href="https://mstdn.science/tags/proflife" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>proflife</span></a></p>
Matt Willemsen<p>“People Have To Be Careful” – Scientists Debunk Claims of a Psychedelic Cannabinoid<br>Despite increasing popularity and claims about its psychedelic effects similar to LSD or psilocybin mushrooms, THC-O-acetate, a cannabinoid derived from delta-8 THC, doesn’t induce significant psychedelic experiences, according to a recent study. THC-O-acetate due to its acetate composition, when heated can produce toxic gas.<br><a href="https://scitechdaily.com/people-have-to-be-careful-scientists-debunk-claims-of-a-psychedelic-cannabinoid/" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://</span><span class="ellipsis">scitechdaily.com/people-have-t</span><span class="invisible">o-be-careful-scientists-debunk-claims-of-a-psychedelic-cannabinoid/</span></a> <a href="https://fedibird.com/tags/Psychedelic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Psychedelic</span></a> <a href="https://fedibird.com/tags/Cannabinoid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Cannabinoid</span></a> <a href="https://fedibird.com/tags/toxic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>toxic</span></a> <a href="https://fedibird.com/tags/gas" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>gas</span></a></p>
CellBioNews<p>Exploring the <a href="https://scientificnetwork.de/tags/evolution" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>evolution</span></a> of <a href="https://scientificnetwork.de/tags/cannabinoid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cannabinoid</span></a> <a href="https://scientificnetwork.de/tags/biosynthesis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>biosynthesis</span></a> in a non-cannabis plant.</p><p><a href="https://scientificnetwork.de/tags/Helichrysum" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Helichrysum</span></a> <a href="https://scientificnetwork.de/tags/cannabigerol" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cannabigerol</span></a></p><p> <a href="https://phys.org/news/2023-05-exploring-evolution-cannabinoid-biosynthesis-non-cannabis.html" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://</span><span class="ellipsis">phys.org/news/2023-05-explorin</span><span class="invisible">g-evolution-cannabinoid-biosynthesis-non-cannabis.html</span></a></p>
Phys.org<p>Referenced link: <a href="https://phys.org/news/2023-04-scientists-potential-human-cannabinoid-exposure.html" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://</span><span class="ellipsis">phys.org/news/2023-04-scientis</span><span class="invisible">ts-potential-human-cannabinoid-exposure.html</span></a><br>Discuss on <a href="https://discu.eu/q/https://phys.org/news/2023-04-scientists-potential-human-cannabinoid-exposure.html" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://</span><span class="ellipsis">discu.eu/q/https://phys.org/ne</span><span class="invisible">ws/2023-04-scientists-potential-human-cannabinoid-exposure.html</span></a></p><p>Originally posted by Phys.org / @physorg_com: <a href="http://nitter.platypush.tech/physorg_com/status/1646194662707806228#m" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">http://</span><span class="ellipsis">nitter.platypush.tech/physorg_</span><span class="invisible">com/status/1646194662707806228#m</span></a></p><p>Scientists evaluate potential human <a href="https://social.platypush.tech/tags/cannabinoid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cannabinoid</span></a> exposure from consuming meat if cattle are fed hempseed cake <a href="https://www.tandfonline.com/doi/full/10.1080/19440049.2023.2187645" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">tandfonline.com/doi/full/10.10</span><span class="invisible">80/19440049.2023.2187645</span></a> <a href="https://phys.org/news/2023-04-scientists-potential-human-cannabinoid-exposure.html" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://</span><span class="ellipsis">phys.org/news/2023-04-scientis</span><span class="invisible">ts-potential-human-cannabinoid-exposure.html</span></a></p>
Scientific Frontline<p>High levels of the body’s own <a href="https://mastodon.social/tags/cannabinoid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cannabinoid</span></a> substances protect against developing <a href="https://mastodon.social/tags/addiction" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>addiction</span></a> in individuals previously exposed to childhood <a href="https://mastodon.social/tags/maltreatment" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>maltreatment</span></a>, according to a new study. Those who had not developed an addiction following childhood maltreatment seem to process emotion-related social signals better.<br><a href="https://mastodon.social/tags/Neuroscience" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Neuroscience</span></a> <a href="https://mastodon.social/tags/Psychiatry" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Psychiatry</span></a> <a href="https://mastodon.social/tags/sflorg" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>sflorg</span></a><br><a href="https://www.sflorg.com/2023/04/ns04122301.html" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">sflorg.com/2023/04/ns04122301.</span><span class="invisible">html</span></a></p>
Anna<p><a href="https://disabled.social/tags/Pain" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Pain</span></a> advice please? </p><p>Is <a href="https://disabled.social/tags/marijuana" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>marijuana</span></a> good for weaning off <a href="https://disabled.social/tags/opiates" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>opiates</span></a>? Is it a replacement? Whole plant or <a href="https://disabled.social/tags/cannabinoid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cannabinoid</span></a> fractions? I don’t think <a href="https://disabled.social/tags/CBD" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>CBD</span></a> on its own could do it.</p><p>Is <a href="https://disabled.social/tags/LDN" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>LDN</span></a> compatible with MJ products? </p><p>What are my options?</p><p>I’ve long term pain that isn’t going away but I don’t want to be on opiates forever, &amp; if Australia goes the same way as the USA in legislating painkillers, I won’t have a choice anyway.</p><p><a href="https://disabled.social/tags/ChronicPain" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>ChronicPain</span></a> <a href="https://disabled.social/tags/Migraine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Migraine</span></a> <a href="https://disabled.social/tags/Endometriosis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Endometriosis</span></a> <a href="https://disabled.social/tags/MECFS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>MECFS</span></a> <br><span class="h-card"><a href="https://a.gup.pe/u/chronicpain" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>chronicpain</span></a></span><br><span class="h-card"><a href="https://a.gup.pe/u/chronicillness" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>chronicillness</span></a></span></p>
Scientific Frontline<p>In <a href="https://mastodon.social/tags/cannabis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cannabis</span></a> trials against <a href="https://mastodon.social/tags/pain" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>pain</span></a>, people who take <a href="https://mastodon.social/tags/placebos" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>placebos</span></a> report feeling largely the same level of pain relief as those who consume the active <a href="https://mastodon.social/tags/cannabinoid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cannabinoid</span></a> substance. <br><a href="https://mastodon.social/tags/Medical" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Medical</span></a> <a href="https://mastodon.social/tags/Pharmaceutical" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Pharmaceutical</span></a> <a href="https://mastodon.social/tags/sflorg" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>sflorg</span></a><br><a href="https://www.sflorg.com/2022/11/med11282202.html" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">sflorg.com/2022/11/med11282202</span><span class="invisible">.html</span></a></p>
Anna<p>Wrote this when less <a href="https://aus.social/tags/PEM" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>PEM</span></a> crashed, but could be a typo/ comprehension minefield:</p><p>Does anyone know if <a href="https://aus.social/tags/CBD" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>CBD</span></a> oil interferes with <a href="https://aus.social/tags/oestrogen" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>oestrogen</span></a>? In general but specifically the <a href="https://aus.social/tags/OCP" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>OCP</span></a> (oral contraceptive pill).</p><p>Would I be better off consuming the whole plant? Perhaps oil from the whole plant? Has anyone had personal experience?</p><p>There is some good evidence that <a href="https://aus.social/tags/cannabis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cannabis</span></a> can stop <a href="https://aus.social/tags/endometriosis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>endometriosis</span></a> from growing outside the uterus altogether, so I’m looking at this as a form of <a href="https://aus.social/tags/pain" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>pain</span></a> relief as well as a treatment and preventative. I don’t know which form and dose is best though.</p><p>The only other treatment for endometriosis is more hormones (which make me sick) and surgery, after which it grows back. Can’t find a doctor specialising in alternative treatments. They all just want to give you a <a href="https://aus.social/tags/Mirena" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Mirena</span></a> <a href="https://aus.social/tags/IUD" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>IUD</span></a> (without anaesthetic!) and surgery after surgery. Sometimes <a href="https://aus.social/tags/hysterectomy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>hysterectomy</span></a> if bad enough. <br> <br>There’s also been some studies about CBD oil and <a href="https://aus.social/tags/LongCovid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>LongCovid</span></a>. Something about switching on the <a href="https://aus.social/tags/cannabinoid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cannabinoid</span></a> system.</p><p>Disclaimer: Yes of course I would get a <a href="https://aus.social/tags/medical" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>medical</span></a> <a href="https://aus.social/tags/marijuana" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>marijuana</span></a> license and buy it legally on prescription.<br>*cough*</p>