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idw_online<p>S3-Leitlinie Chronische Lymphatische Leukämie umfassend aktualisiert, Neuerungen zur Therapie bei Richter Transformation aufgenommen: www.krebsgesellschaft.de/pressemitteilungen-2025/s3-leitlinie-cll.html <br><a href="https://idw-online.social/tags/CLL" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>CLL</span></a> <a href="https://idw-online.social/tags/Onkologie" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Onkologie</span></a> <a href="https://idw-online.social/tags/Leitlinie" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Leitlinie</span></a> @krebsgesellschaft.bsky.social<br><a href="https://nachrichten.idw-online.de/2025/02/11/s3-leitlinie-chronische-lymphatische-leukaemie-umfassend-aktualisiert" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">nachrichten.idw-online.de/2025</span><span class="invisible">/02/11/s3-leitlinie-chronische-lymphatische-leukaemie-umfassend-aktualisiert</span></a></p>
Tiskovec.cz<p>Skvělá zpráva z FN Brno! 🎉 Publikace &amp;quot;Recommendations for TP53 gene analysis in CLL&amp;quot; se umístila na 3. místě v seznamu The Best of Leukemia 2024. Tato doporučení jsou klíčová pro diagnostiku a léčbu chronické lymfocytární leukémie. Gratulujeme týmu za jejich úžasný úspěch! <a href="https://mastodonczech.cz/tags/FNBrno" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>FNBrno</span></a> <a href="https://mastodonczech.cz/tags/Leukemia" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Leukemia</span></a> <a href="https://mastodonczech.cz/tags/TP53" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>TP53</span></a> <a href="https://mastodonczech.cz/tags/Genetics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Genetics</span></a> <a href="https://mastodonczech.cz/tags/CLL" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>CLL</span></a> </p><p>👉 Více informací najdete zde:<br><a href="https://tiskovec.cz/clanky/velky-uspech-molekularnich-geneticek-z-fn-brno-jejich-publikace-se-umistila-mezi-nejuspesnejsimi-clanky-roku-2024-v-casopise-leukemia-7?utm_source=mastodon_czech&amp;amp;utm_medium=social&amp;amp;utm_campaign=new_article" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">tiskovec.cz/clanky/velky-uspec</span><span class="invisible">h-molekularnich-geneticek-z-fn-brno-jejich-publikace-se-umistila-mezi-nejuspesnejsimi-clanky-roku-2024-v-casopise-leukemia-7?utm_source=mastodon_czech&amp;amp;utm_medium=social&amp;amp;utm_campaign=new_article</span></a></p>
tiskovec<p>Skvělá zpráva z FN Brno! 🎉 Publikace &amp;quot;Recommendations for TP53 gene analysis in CLL&amp;quot; se umístila na 3. místě v seznamu The Best of Leukemia 2024. Tato doporučení jsou klíčová pro diagnostiku a léčbu chronické lymfocytární leukémie. Gratulujeme týmu za jejich úžasný úspěch! <a href="https://mastodon.social/tags/FNBrno" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>FNBrno</span></a> <a href="https://mastodon.social/tags/Leukemia" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Leukemia</span></a> <a href="https://mastodon.social/tags/TP53" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>TP53</span></a> <a href="https://mastodon.social/tags/Genetics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Genetics</span></a> <a href="https://mastodon.social/tags/CLL" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>CLL</span></a> </p><p>👉 Více informací najdete zde:<br><a href="https://tiskovec.cz/clanky/velky-uspech-molekularnich-geneticek-z-fn-brno-jejich-publikace-se-umistila-mezi-nejuspesnejsimi-clanky-roku-2024-v-casopise-leukemia-7?utm_source=mastodon_social&amp;amp;utm_medium=social&amp;amp;utm_campaign=new_article" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">tiskovec.cz/clanky/velky-uspec</span><span class="invisible">h-molekularnich-geneticek-z-fn-brno-jejich-publikace-se-umistila-mezi-nejuspesnejsimi-clanky-roku-2024-v-casopise-leukemia-7?utm_source=mastodon_social&amp;amp;utm_medium=social&amp;amp;utm_campaign=new_article</span></a></p>
Tinu - Empress of Twerk<p>Just sharing that I, </p><p>a <a href="https://mastodon.social/tags/LongCOVID" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>LongCOVID</span></a> and <a href="https://mastodon.social/tags/Cancer" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Cancer</span></a> patient, </p><p>have been coughing and had ANOTHER fever</p><p>as a result of my <a href="https://mastodon.social/tags/oncology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>oncology</span></a> appointment. </p><p>Where only 50% of the people were masked. </p><p>At JPS Oncology. In Texas. </p><p>Where my appointment was expedited. Due to a mandatory ER appointment. </p><p>Where also few masked.</p><p>And I went in, as mentioned, for a fever.</p><p>As I have a mandatory ER (not UC) visit </p><p>whenever my fever goes over 100.5. </p><p>As the cancer I have <a href="https://mastodon.social/tags/CLL" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>CLL</span></a> advances when I have an infection.</p>
Tinu - Empress of Twerk<p>It’s that there’s no help for disease either. You have <a href="https://mastodon.social/tags/LongCOVID" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>LongCOVID</span></a>? Well fuck you. 🤷🏾‍♀️</p><p>I was lucky (I can’t believe I’m saying this) that the COVID re-activated the cancer <a href="https://mastodon.social/tags/CLL" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>CLL</span></a> - in that modern oncology treats your whole body. </p><p>Therefore oncologist- who I pay for out of pocket - continued my oxygen prescription. </p><p>Expensive but saved my life, without a doubt. </p><p><a href="https://gofund.me/95d3f7be" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://</span><span class="">gofund.me/95d3f7be</span><span class="invisible"></span></a></p>
The Virtual Memories Show<p>Just posted a new <a href="https://mastodon.social/tags/Substack" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Substack</span></a>! It's got reflections on family &amp; time, links by/re <a href="https://mastodon.social/tags/AlJaffee" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>AlJaffee</span></a> <a href="https://mastodon.social/tags/RutuModan" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>RutuModan</span></a> <span class="h-card"><a href="https://mstdn.social/@christopher_brown" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>christopher_brown</span></a></span> <a href="https://mastodon.social/tags/EdwardJayEpstein" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>EdwardJayEpstein</span></a> <a href="https://mastodon.social/tags/Bookshop_Org" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Bookshop_Org</span></a> <a href="https://mastodon.social/tags/CLL" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>CLL</span></a>, a new <a href="https://mastodon.social/tags/podcast" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>podcast</span></a> w/#NoahVanSciver, &amp; more, so go read, share &amp; subscribe: <a href="https://vmspod.substack.com/p/trainwriting" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://</span><span class="ellipsis">vmspod.substack.com/p/trainwri</span><span class="invisible">ting</span></a></p>
The Virtual Memories Show<p>New Virtual Memories <a href="https://mastodon.social/tags/substack" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>substack</span></a> is out! This one's got a new <a href="https://mastodon.social/tags/podcast" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>podcast</span></a>, my Dostoevskian whiplash &amp; finding a tribe, some great links, the restirring of <a href="https://mastodon.social/tags/art" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>art</span></a> &amp; the rites of spring, &amp; some neckstands. Read, share &amp; subscribe! <a href="https://vmspod.substack.com/p/tribe-of-zero" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://</span><span class="ellipsis">vmspod.substack.com/p/tribe-of</span><span class="invisible">-zero</span></a></p><p><a href="https://mastodon.social/tags/books" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>books</span></a> <a href="https://mastodon.social/tags/bookstodon" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>bookstodon</span></a> <a href="https://mastodon.social/tags/CLL" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>CLL</span></a> <a href="https://mastodon.social/tags/stagezero" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>stagezero</span></a> <a href="https://mastodon.social/tags/illustration" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>illustration</span></a> <a href="https://mastodon.social/tags/painting" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>painting</span></a></p>
𝕵𝖆𝖒𝖎𝖊 🦠🔬💉<p><a href="https://mastodon.social/tags/covid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>covid</span></a> <a href="https://mastodon.social/tags/Leukemia" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Leukemia</span></a> <a href="https://mastodon.social/tags/CLL" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>CLL</span></a></p><p>疫情開始以來偶爾會有些患者在因Covid-19確診住院期間突然出現慢性淋巴細胞白血病（CLL），目前尚未確定發病機轉，該篇文章闡述他們覺得可能的發病幾轉，並指出未來需要監控病人白血球細胞的狀態變化</p><p>CLL： 一種常見的白血病，主要影響B細胞</p><p>🔗：<a href="https://www.mdpi.com/2077-0383/12/3/998" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://www.</span><span class="">mdpi.com/2077-0383/12/3/998</span><span class="invisible"></span></a></p>
Gene Regulation<p>Our new preprint! Nucleosome repositioning in chronic lymphocytic leukaemia (CLL) <a href="https://www.biorxiv.org/content/10.1101/2022.12.20.518743v1" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">biorxiv.org/content/10.1101/20</span><span class="invisible">22.12.20.518743v1</span></a><br>▶️Nucleosome changes at cancer-sensitive regions allow patient stratification <br>▶️Nucleosome repeat length (NRL) decreases with <a href="https://genomic.social/tags/cancer" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cancer</span></a> aggressiveness<br>▶️Interplay with <a href="https://genomic.social/tags/methylation" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>methylation</span></a>, <a href="https://genomic.social/tags/TFbinding" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>TFbinding</span></a> and more!</p><p><a href="https://genomic.social/tags/CLL" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>CLL</span></a>, <a href="https://genomic.social/tags/nucleosome" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>nucleosome</span></a>, <a href="https://genomic.social/tags/leukaemia" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>leukaemia</span></a>, <a href="https://genomic.social/tags/chromatin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>chromatin</span></a></p>
Ann Howarth<p>This is an interesting discussion, particularly for patients with B cell lymphomas. Some interesting comments about ongoing Evusheld efficacy (not good) as well risks associated with long-term infections. <a href="https://mastodonapp.uk/tags/CLL" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>CLL</span></a> <a href="https://mastodonapp.uk/tags/BloodCancer" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>BloodCancer</span></a> <a href="https://mastodonapp.uk/tags/Evusheld" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Evusheld</span></a></p><p><a href="https://www.ajmc.com/view/breakthrough-covid-19-infection-in-10-of-patients-with-blood-cancer-lls-data-shows" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">ajmc.com/view/breakthrough-cov</span><span class="invisible">id-19-infection-in-10-of-patients-with-blood-cancer-lls-data-shows</span></a></p>
Kerry J. Laing, PhD<p>After a very busy couple of years, it is nice to see the finished product. This is probably our final <a href="https://mstdn.science/tags/publication" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>publication</span></a> for 2022, from a collaboration with Dr Chaitra Ujjani (perhaps not on Mastodon). TL;DR? <a href="https://mstdn.science/tags/CLL" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>CLL</span></a> patients have lower antibody and <a href="https://mstdn.science/tags/Tcell" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Tcell</span></a> responses to <a href="https://mstdn.science/tags/CovidVaccines" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>CovidVaccines</span></a> especially when on B cell targeting therapy. So, how should we overcome this to make safe and effective vaccines for these patients?<br> <a href="https://doi.org/10.1182/bloodadvances.2022009164" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://</span><span class="ellipsis">doi.org/10.1182/bloodadvances.</span><span class="invisible">2022009164</span></a></p>
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